How Often Frontline For Dogs

For the best flea control, treat each of your dogs and cats once a month. When properly sprayed, FRONTLINE PLUS keeps fighting fleas for at least a month. If you live in a region where paralysis ticks are present, treat your dog with FRONTLINE PLUS FOR DOGS every two weeks to prevent paralysis ticks. Apply FRONTLINE SPRAY every three weeks to your cat if you live in a paralysis tick zone to protect it from paralysis ticks.

Can I use Frontline spot on frequently?

The presence of fleas quickly after using the remedy is a sign that it is effective. By overstimulating fleas’ nerve systems, FRONTLINE Spot On kills them, causing disoriented, hyperexcited fleas to rise to the surface of the pet’s coat and become more noticeable.

It’s also crucial to understand that it’s common for your pet to have fleas since they take up fresh fleas from the surroundings that are emerging from pupae. Within 24 hours of jumping onto your treated pet, these will be destroyed.

The presence of a lot of fleas, though, indicates an infestation in your home’s environment. Flea eggs in the environment may be hatching into a large number of fleas. Even if you have sprayed an insect growth regulator (IGR) on your house, the pupae will not be killed. An IGR only eradicates eggs and larvae, so until all adult fleas have emerged from their pupae and entered the environment, you will still find fresh fleas on your pet. To reduce the flea population on your pet, treat them every four weeks.

No. Where your pet can’t lick it off, at the base of the neck between the shoulder blades, you must apply it straight to the skin of the animal, not on their hair.

Yes, they can do so starting 48 hours after applying. Even if your pet gets wet, FRONTLINE Spot On is water proof and will continue to work. We advise applying FRONTLINE Spot On every four weeks if your pet bathes or swims more than once a week.

each quarter. You should apply treatment year-round because ticks have been discovered to be active even during the chilly winter months. You might still find some ticks on your pet because FRONTLINE Spot On is not a tick repellant. Within 48 hours, they should be put to death.

Fipronil is an ingredient in several flea-treatment treatments. Are these items interchangeable with FRONTLINE Spot On?

No, look at what the label says. They differ even if they have the same component.

How long does a dog’s frontline treatment last?

Frontline Plus also contains methoprene in addition to fipronil. It is an analog of the juvenile hormone, so

because it imitates the hormone that keeps fleas “young,” or juvenile, in activity. When this substance is

When flea larvae or their surroundings are directly exposed to an agent, the larvae are unable to undergo metamorphosis.

When given to female fleas, methoprene also exhibits ovicidal and embryocidal effects. Keep in mind Frontline

Comparing Plus for Cats and Kittens to the canine equivalents, Plus for Cats and Kittens includes a larger amount of (s)-methoprene.

Within 24 hours after application, Frontline Plus and Top Spot are carried throughout the body of the treated pet. Those are

transported in the skin’s oil layer and deposited into the glands that release oil, or sebaceous, on the skin.

the medication for the entire treatment month. The product is also sprayed liberally over the entire body.

In less than 24 hours, Frontline eliminates 98 to 100% of adult fleas that are already present. It can continue to work well against

In cats and dogs, fleas can be present for up to six weeks. However, it is advised to use a monthly application to be sure

The methoprene component of Frontline is effective against both larvae and eggs in addition to killing adult fleas.

To ensure effective environmental flea management, the life cycle must be broken at several phases. This flea inhibition

According to development, there is little to no chance of a re-infestation on dogs for 12 weeks and cats for 6 weeks.

The substance will shed fur into the locations where it localizes in the skin’s outer layer and hair as well.

The animal will likely have the biggest concentration of larvae where it spends the most time.

“In less than 24 hours, Frontline eliminates 98 to 100% of adult fleas that are already present. It can continue to work

Deer ticks, Lone Star ticks, Brown dog ticks, and American dog ticks for at least a month. But it might take as long as

Ticks on dogs need to die after 48 hours. Merial, the product’s maker, recommended daily animal inspections if you

reside in a tick-prone location, as some diseases carried by ticks can be transmitted in just 48 hours.

Because Frontline is deposited in the sebaceous gland, it keeps working even after your pet bathes or swims.

glands,. However, it must only be used on a dry animal. For 24 to 48 hours, animals shouldn’t be bathed.

after using Frontline to give the medication time to circulate throughout the body and enter the glands. From

so bathing, swimming, or sun exposure won’t have an impact on the product’s effectiveness.

Frontline is also approved for used to quickly get rid of chewing lice. Treatments should be repeated every month.

Frontline is only marginally absorbed into your pet’s body when given externally, thus toxicity or poisoning following

Application as usual is unlikely. Compared to human nerve receptors, the substance is more selective for the

Regarding negative Frontline side effects, the following is stated on the medication’s label:

“Even though they are uncommon, individual reactions might happen after applying any pesticide product. Pets could occasionally go through

irritation where the product was applied. If symptoms continue or worsen within a few days of

Hair loss, redness, or itching in the area where the product was administered are all signs of skin irritation. Rare occasions

On occasion, skin responses have been reported by pet owners. The product’s harsh taste is probably present if animals lick it.

While Frontline spray has no such restrictions, Frontline spot-ons can be used safely in breeding, pregnant, and lactating cats and dogs.

claim. Puppies and kittens can start using any formulation at eight weeks old. Rabbits are extremely poisonous to fipronil.

and should never be applied to this animal since it can cause death.

The spot-on formulations are applied to dry (not wet) animals’ skin in a single location once a month, between the

Applying the spray while wearing latex kitchen gloves and holding the bottle upright is recommended. The animal’s fur

should be fluffed with one hand to reveal the skin, then the back, sides, stomach, and legs should be sprayed.

pet’s neck and shoulders until the fur is damp to wet. It is advised that the region around the head and eyes be

The typical application volume is one to two pumps per pound of body weight, while long-haired pets may require more.

The greater rate can be needed for coats. Owners are recommended to properly wash their hands and any exposed skin with soap and water.

To discuss the best flea or tick prevention for your pet, please talk to your veterinarian.

Merial Ltd., Duluth, Georgia, Frontline Plus, Frontline Top Spot, and Frontline Spray Labels. British Veterinary Dermatology Study Group

Adverse Experiences Report, 1998–2003, 2004. Australian Veterinary and Pesticides Authority

Imidacloprid, Permethrin, and Fipronil as Topical Treatments to Repel and Kill American

Suppl Compend Contin Educ Pract Vet. 24:4(B), pp. 17–20, 2002. Dog Ticks (Dermacentor variabilis) on Dogs.

Fipronil Fact Sheet: National Pesticide Information Center, National Pesticide Telecommunications Network.

Can Frontline be used three times per month?

Some of the more frequent inquiries I’ve been asked lately at the clinic about f and its application to prevent flea and tick infestations in animals. The quality of Frontline Plus sold by internet pharmacies like 1800petmeds and if it is the same as that used and sold by veterinarian offices are two major concerns I frequently have. The fact is that Frontline Plus is a prepackaged drug made by Merial, the same drug that 1-800-PetMeds and your neighborhood vet also carry.

Another typical query is, “Why is my pet still infested with fleas after using Frontline?

after a few months in a row. Flea treatments frequently fail because to inappropriate application or, more frequently, a failure to treat the pet’s surroundings, which includes the home and yard, where 80% of the flea life cycle takes place. Similarly, some products, however, will work on some pets more effectively than others. I would advise hiring a professional exterminator to treat your home and/or switching to a different product like Advantage if fleas persist despite proper treatment of the home and use of Frontline Plus for a number of months.

Many vets will use the treatment more frequently than once per month, sometimes even once every two to three weeks, if a pet still has fleas. However, this procedure is sometimes viewed as “Using the substance in this manner is off-label use, and I wouldn’t do it without first consulting your pet’s veterinarian. If a client is currently taking Revolution or Advantage or another topical medication, it is okay to switch to Frontline Plus 3–4 weeks following the date of the last application of the prior medication. Despite the fact that Frontline Plus is advertised as being waterproof, I typically urge clients to wait at least 24 to 48 hours before bathing their pet. Frontline Plus side effects are uncommon, however they can include hair loss, skin irritation where it was applied, stomach problems, immunological blood reactivity, and neurological reactions like seizures. Again, they are really uncommon since the majority of pets accept this product pretty well.

Is Frontline given on a monthly basis?

  • Promotes long-lasting and quick-acting protection from ticks and fleas.
  • Two active substances were used in the formulation to help break the flea life cycle.
  • kills ticks, chewing lice, adult fleas, flea eggs, and flea larvae.
  • Apply only once each month.
  • designed to become waterproof after 24 hours.

Frontline Plus Flea & Tick Spot Treatment for Small Dogs, 5-22 lbs. can help shield your dog from insects. This remedy eliminates chewing lice, ticks, adult fleas, flea eggs, and flea larvae. Fipronil and (S)-methoprene, two of the formulation’s active constituents, assist in severing the flea life cycle and preventing further infestations. Additionally, it is created to be effective quickly and last for 24 hours without drying out. For 30 days, one simple topical application is effective. Small dogs weighing 5 to 22 pounds respond paw-fectly to this medication.


Your pet may have some brief itchiness where the medication was applied. Within a few days of application, visit your veterinarian right away if symptoms continue or worsen.

Watch your pet after the procedure. ANY pesticide product used on pets may cause sensitivities. Before using the product, please read the complete manufacturer’s insert. approved for usage in dogs that are breeding, expecting, or nursing. Before usage on sick, medicated, or old animals, consult a veterinarian. After the product has dried, wait 24 hours before allowing cats near treated canines. If a cat ingests or applies the substance, call your veterinarian right once.


  • Away from your torso and face, snap the Frontline applicator’s tip open.
  • Place the applicator tip on the skin by parting your pet’s hair so that you can see the skin between the shoulder blades.
  • Apply the full contents in a single place on the skin each month using the squeeze applicator.
  • Before bathing or swimming, wait 24 hours.

Additional Tips

  • Get the dog’s collar off.
  • Apply in one non-lickable location between your dog’s shoulder blades.
  • Try not to touch the wet application area.
  • Before giving your dog a bath or going swimming, wait 24 hours to let the solution dry.
  • Each of your dogs should receive a full dose.

Frequency of Application

  • FRONTLINE Plus effectively stops the flea life cycle when applied monthly and manages tick and chewing lice infestations. For 30 days, do not reapply for FRONTLINE Plus.
  • For up to three months, FRONTLINE Plus destroys adult fleas, flea eggs, and flea larvae. For up to three months, FRONTLINE Plus also stops the growth of all flea stages. FRONTLINE Plus can prevent fleas for up to three months, but a monthly application may be necessary if there is a significant chance of reinfestation or if the pet has fleas that could lead to flea allergic dermatitis.
  • Ticks are eradicated by FRONTLINE Plus for at least a month. Where tick management is required, a once-monthly application is advised. All tick life stages are eliminated by FRONTLINE Plus (larva, nymph and adult).
  • Ticks that could spread Lyme disease, Rocky Mountain spotted fever, ehrlichiosis, babesiosis, anaplasmosis, and other tick-borne diseases are killed by FRONTLINE Plus.
  • Chewing lice are killed with FRONTLINE Plus for at least a month. Where chewing lice control is required, a once-monthly application is advised.
  • Sarcoptic mange infestations can be managed with the help of FRONTLINE Plus. It is advised to use multiple monthly treatments to get rid of mites.

Can Frontline be used every two weeks?

For the prevention of paralysis ticks on dogs and the management of brown dog ticks, FRONTLINE PLUS FOR DOGS should be treated either monthly or every two weeks. For the prevention of paralysis ticks on cats and dogs, FRONTLINE SPRAY should be used every three weeks, or once a month for the prevention of brown dog ticks.