How can I keep my dog from getting car ill (motion sickness)?
Car sickness in dogs can be lessened by making sure their stomachs are empty prior to the journey. Frequently stopping can also be beneficial. However, Cerenia is the medication of choice among vets for halting canine motion sickness vomiting. 2 It is the first and only veterinary drug for motion sickness-related vomiting in dogs that has received FDA approval.
Cerenia is non-sedating, therefore it shouldn’t make you feel sleepy. Therefore, your companion ought to be the same when you get at your location. This is distinct from drugs like Dramamine and Benadryl, which may make you drowsy and aren’t FDA-approved for treating dog vomiting.
Maropitant citrate, an antagonist of the neurokinin-1 (NK-1) receptor, is the active component of Cerenia. Maropitant inhibits the central nervous system neurotransmitter substance P, which is involved in vomiting. Maropitant can stop vomiting by preventing the NK1 receptor from recognizing substance P. Cerenia gets to work right away to stop or stop your pet’s vomiting. It lasts for roughly 24 hours.
According to post-approval adverse medication experience reporting, the following adverse events have occurred. Anorexia, depression/lethargy, hypersalivation, vomiting, and diarrhea are the top 5 adverse effects observed in dogs, listed in decreasing order of frequency. See the prescribing information for further details on possible side effects.
Whether Cerenia is prescribed to stop severe vomiting at home or to stop vomiting because of motion sickness in a car, the dosage to be administered varies. Make careful to adhere to your veterinarian’s advice regarding Cerenia. Give your dog Cerenia with a little amount of food at least two hours before a trip to minimize motion sickness-related vomiting. This can be done once per day for up to two days straight. You can take Cerenia once daily to prevent acute vomiting at home:
- puppies aged 2 to 7 months, every day for up to 5 days straight
- To dogs older than 7 months, every day for whatever long your doctor has recommended
Puppies older than 4 months old can be given Cerenia to reduce motion sickness-related vomiting. Puppies 2 months and older can receive Cerenia to prevent acute vomiting.
Veterinarians can prescribe the drug Cerenia for their patients. If you think Cerenia might benefit your pet, discuss it with your veterinarian. The price of Cerenia can change depending on your pet’s weight and diagnosis, among other things. For further information, talk to your vet.
The first medication for cat vomiting that the FDA has approved is called Cerenia injectable. Your veterinarian gives it to you as an injection. If you are worried about your cat’s vomiting, talk to your veterinarian.
See the prescribing information for important safety information. Use Cerenia Injectable to treat acute vomiting in cats 4 months of age and older. Use subcutaneously or intravenously to treat acute vomiting in dogs 2 to 4 months of age. Use Cerenia tablets for dogs 2 months of age and older to treat acute vomiting as well as for dogs 4 months of age and older to avoid vomiting brought on by motion sickness. Cats and dogs with gastrointestinal obstruction or those who have consumed poisons have not been studied for safe use. Use with caution in canines and felines with liver disease. A typical side effect of injections is pain or vocalization. Topical exposure can cause localized allergic skin reactions in humans, and continued or extended exposure can cause skin sensitization.
Johnson & Johnson Consumer Inc. or one of its associated companies has registered Benadryl as a trademark. The registered trademark for Dramamine belongs to Prestige Brands Holdings, Inc. or one of its licensees. The registered trademark for Bonine belongs to Insight Pharmaceuticals LLC.
Dramamine, Bonine, Benadryl, and herbal supplements haven’t undergone FDA-CVM testing or approval for use in canines.
- Boucher JF, Conder GA, Sedlacek HS, and Clemence RG. Maropitant, a selective neurokinin one receptor antagonist, was tested in two randomized clinical studies for its effectiveness and safety in preventing motion sickness-related vomiting. 2008;31(6):528-532 in J Vet Pharmacol Ther.
- Cerenia A&U Report, March 2020, data on file. Inc. Zoetis
- Pet Owner Quantitative Research Report on Motion Sickness and Noise Aversion, December 2018.
Only US citizens are meant for the product information offered on this website. The products covered in this article might not have marketing approval or might have different product labels in other nations. The material on animal health offered here is only for educational reasons and is not meant to take the place of discussions with an expert in the field of animal healthcare. Every choice about the treatment of a veterinary patient must be discussed with a veterinarian who is knowledgeable about the patient’s particular needs.
Cancerenia perhaps make dogs drowsy?
Drowsiness, lethargy, a lack of appetite, and diarrhea are possible side effects of Cerenia. Before embarking on the actual journey, it is advisable to take your pet on a “test drive” if you are administering the prescription to them for the first time. In this way, you can keep track of how your dog is responding to the drug and decide if it’s a good long-term solution.
Use of Cerenia in puppies younger than 16 weeks is not advised. Additionally, if your dog has liver issues, you should take additional precautions. Additionally, if your pet has never taken Cerenia before, he could experience a severe adverse response. Hives, face swelling, and/or breathing problems are a few of these symptoms. Anywhere you travel, it’s crucial to keep in mind that if this should happen, you’ll need emergency veterinarian care. Make sure there is sufficient help available nearby.
Similar adverse symptoms, such as lack of appetite, bloody stools, and diarrhea, may occur in your pet if they unintentionally overdosed on Cerenia. Make sure to keep all medications out of your pet’s reach and to follow the medication schedule as directed by the veterinarian. There can be internal adverse effects in addition to any observed exterior symptoms.
Not every dog is a good candidate for Cerenia by default. It depends on other prescriptions, the patient’s age, the breed, their general health, and any other physical issues or risks that your vet notices. Discuss any drugs or dietary supplements your pet is taking with their veterinarian. He or she will assess whether Cerenia is a good solution for your pet or whether there are any better options.
How do dogs react to cerenia?
The brain then transmits impulses that cause vomiting when this happens. These signals are suppressed by Cerenia. It actively competes with substance P, a neurotransmitter that causes nausea and vomiting. By doing this, your dog doesn’t feel or become ill.
Do dogs get sleepy from anti-nausea medication?
An antiemetic called maropitant citrate (trade name: Cerenia) is used to treat motion sickness and vomiting in canines and felines. It may also have a minor analgesic effect.
It is “off label” or “extra label” to use the tablets to treat nausea and vomiting in cats. In veterinary medicine, many medications are frequently used for off-label uses. In these situations, carefully adhere to your veterinarian’s instructions and warnings as they may change dramatically from those on the label.
How is maropitant citrate given?
Maropitant citrate is administered as a tablet or an intramuscular injection as directed by a veterinary specialist. Feed your pet a modest meal three hours before traveling, and then give them maropitant citrate an hour later (two hours before traveling), if prescribed to avoid motion sickness. This drug can help avoid vomiting if it is administered with a modest meal. Avoid wrapping the tablet in food too tightly as this can prevent the medication from being adequately absorbed. In about 1 to 2 hours, this medication will start to work, and improvements in clinical indicators should follow.
Give maropitant citrate before the chemotherapeutic drug if it is being used to prevent chemotherapy-related vomiting.
When giving this drug to patients, exercise caution because topical exposure may result in adverse reactions. Whenever this happens, wash with soap and water.
What if I miss giving my pet the medication?
As soon as you recall, administer the missed dose; follow that with the advised interval between doses. Never administer additional dosages or two doses at once to your pet.
Are there any potential side effects?
When using the larger doses needed to treat motion sickness, the most frequent adverse effects include hypersalivation and vomiting. When using the injectable form, it is possible for the injection site to experience pain or swelling. Lethargy, decreased appetite, diarrhea, allergic reactions, clumsy walking, and convulsions are more uncommon side effects. Cats may also experience irregular breathing, recumbency (lying down and unable to get up), vomiting, panting, and muscle spasms in addition to these uncommon adverse effects. The effects of this quick-acting medicine should wear off after 24 hours, though they may last longer in animals with liver or renal illness.
Are there any risk factors for this medication?
Pets under 8 weeks old, animals with gastrointestinal obstructions, or animals that have swallowed poisons shouldn’t use this medication. In animals with liver or heart illness, as well as those that are lactating or pregnant, it should be administered with caution. When taking the higher, motion-sickness dose of maropitant citrate in puppies younger than 16 weeks old, caution should be exercised because bone marrow suppression has been reported in these circumstances.
Are there any drug interactions I should be aware of?
When administered with maropitant citrate, the drugs chloramphenicol, phenobarbital, erythromycin, ketoconazole, itraconazole, and NSAIDs should all be used with caution.
Tell your vet about any medications your pet is receiving, including vitamins, supplements, and herbal treatments.
Is there any monitoring that needs to be done with this medication?
While your pet is receiving this medication, no special monitoring is necessary. To ensure that the drug is having the desired effect, your veterinarian may check on your pet.
How do I store maropitant citrate?
Tablets of maropitant citrate should be kept dry and at room temperature.
With permissible excursions between 15C and 30C (59F-86F), the injectable solution should be stored between 20C and 25C (68F-77F). The injectable should be kept in the refrigerator between 2C and 8C (36F-46F) after the vial has been punctured, and it should be used within 90 days. Avoid freezing.
What should I do in case of emergency?
Call your veterinarian’s office right away if you think your pet may have taken too much medication or is having an unfavorable reaction to it. Follow their instructions for contacting an emergency facility if they are not readily available.
What negative consequences does Cerenia have?
Although they are rare, adverse effects with Cerenia for dogs may include:
- muscle tremors.
- decrease in appetite.
How soon does Cerenia start to work in dogs?
What is the purpose of cerenia? The use of Cerenia is indicated on the label for treating and preventing motion sickness and vomiting. Cerenia has recently been discovered to be successful in managing pain and treating a number of inflammatory disorders.
Describe Cerenia. Substance P, a neurotransmitter involved in vomiting, is blocked by Cerenia in the brain, which causes it to act. Peripherally, it also has some impact on the contractions and inflammation of the small intestine.
How is Cerenia administered? What happens if a dose is missed? The typical dosage for cerenia is one dose per day. Give the missing dose if it is less than 12 hours late if a dose is missed. Skip the dose and resume your regular schedule with the next dose if the gap between doses is less than 12 hours. Before repeating Cerenia therapy, there must be a two-day rest period following five days of use. While it’s advised to administer with a modest bit of food, stay away from fatty goodies as this could reduce effectiveness. Within an hour of administration, Cerenia typically starts to work.
Are there any typical side effects from using Cerenia? At larger doses, drooling, loss of appetite, diarrhea, and drowsiness may occur. Some people experience pain at the injection site.
People who shouldn’t take Cerenia Patients with liver problems or puppies under 11 weeks old should use caution.
What medicines ought not be administered alongside Cerenia? When used with phenobarbital, thyroid hormone, and non-steroidal anti-inflammatories, side effects can be more frequent.
How soon can my dog eat after taking Cerenia?
Giving your dog any form of medication or drug can be terrifying, but Cerenia is safe if you adhere to the instructions. You don’t need to worry because it has FDA approval as being safe for your dog. Depending on what you are treating, there are differences in the dosage and frequency of medicine administration to dogs. The medicine should be used once daily for two consecutive days if you’re treating motion sickness. We’ll talk more about this below. If it needs to be given again, you must wait three days before doing so for a second time that lasts two days.
It can be used once daily for five days straight to treat acute vomiting. Further on, we have outlined the amounts you must give your dog based on their weight. Always take the Cerenia medication with a modest amount of food, like some deli meat. It must be given to your dog with an empty stomach at least an hour before.
What You Should Tell Your Vet Before They Prescribe Cerenia
Cerenia can be quite effective at reducing vomiting, but in a few circumstances, you should let your veterinarian know about any prior illnesses. You must inform your veterinarian if your dog has been diagnosed with liver malfunction, kidney disease, seizures, epilepsy, or cardiovascular issues. Additionally, if your dog is already receiving medicine of any kind, you should let your veterinarian know because some drugs may interact with Cerenia.
Another item to mention to your veterinarian is whether or not your dog is pregnant, lactating, or nursing. You’ll want to be cautious because there haven’t been many research on how Cerenia affects dogs who are pregnant, breastfeeding, or nursing. Additionally, if your dog has ever consumed a poisonous substance, they can be given another antiemetic medication in place of Cerenia.
These warnings are not designed to terrify you, and Cerenia is still safe, according to us. However, it is always advisable to err on the side of caution and inform your veterinarian if there is anything you believe may prevent your pup from using Cerenia. After all, you want them to be secure!
How To Give Cerenia To Your Dog
The dosage of Cerenia depends on the age at which it can be administered to dogs as well as the intended use. The youngest age at which you can provide Cerenia to a patient is 2 months old if you’re treating acute vomiting associated with a condition or as a side effect of another medication, as we previously indicated. But your dog needs to be 4 months old if you’re using Cerenia to cure motion sickness.
Cerenia is available as oral tablets in various dosages, including 16, 24, 60, and 160 mg. Although your dog’s stomach should be empty one hour before you deliver Cerenia, the tablets should be given two hours prior to travel and combined with some food.
The quantity you give your dog depends on how much they weigh. The dose is currently prescribed as 2mg/kg body weight, administered once daily, and repeatable the following day. If it is required once more, you must wait three days before giving Cerenia over a two-day period. According to the size of your dog, we have listed the dose quantity below.
Size & Weight
- 2 to 2 and a half of a 16-mg tablet
- 2.3–3.3 pounds and half a 24 mg tablet
- one 16-mg tablet, between 3.4 and 4.4 pounds
- one 24-mg tablet, between 4.5 and 6.6 pounds
- two 16-mg pills, between 6.7 and 8.8 pounds
- 2.24 milligrams of two 24-pound pills
- One 60-mg tablet weighs between 13.3 and 16.5 pounds.
- 1/2 a 160-mg tablet, between 16.6 and 22.0 pounds
- 22.1 to 33 lbs.
- two tablets of 60 mg
- one 160-mg tablet, between 33.1 and 44.0 pounds
- one and a half 160-mg tablets, between 44.1 and 66.0 pounds
- two 160-mg pills, between 66.1 and 88.0 pounds
- three 160-mg tablets, weighing 88.1 to 132.0 pounds.
The dosages are slightly different if you’re using Cerenia to treat acute vomiting brought on by a disease or another type of treatment. If your dog is between the ages of 2 and 7 months, you should administer their dose once daily, again based on weight, and repeating this dose for five days in a row. If your dog is older than 7 months old, you can administer their dose daily until the acute vomiting stops. The suggested doses are listed below for your convenience.
- 2.2 to 8.8 kg a 16-mg pill, half
- 8.9 to 17.6 pounds one 16-mg pill
- One 24-mg tablet weighs between 17.7 and 26.4 pounds.
- two 24-mg pills, between 26.5 and 52.8 pounds
- between 52.9 and 66.0 pounds one 60-mg pill
- two 60-mg pills, between 66.1 and 132.0 pounds
It has been suggested that you give your dog the Cerenia pill wrapped in a small piece of deli meat. The Cerenia may take longer to take effect if the pill is smuggled into other meals like cheese or sausage.
What To Do If You Miss A Dose
Give your dog’s Cerenia as soon as you remember if you forget to give them a dose. If the next dose is only a few hours or less away, skip the dose you missed and administer the subsequent dose as scheduled. Even if you missed a dose of Cerenia, you should never take two doses at once.
What To Do In Case Of A Cerenia Overdose
If your dog accidentally overdoses on Cerenia, you should take them to the vet so they can get treated. Although it should be safe, some dogs may have negative reactions to a high dose of Cerenia. Among other things, overdose can have the following effects: tremors, bloody stool, diarrhea, and erratic breathing. Always seek medical advice and take your dog to the doctor if you suspect an overdose.
About Joanne Spencer
My lifelong love of animals inspired me to pursue a career in training and behavior. As an expert on animals, I’m dedicated to enhancing the bonds between people and animals in order to increase their pleasure.